What is Accupril?

Accupril is used to treat high blood pressure, or hypertension, and heart failure. It is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme.

Accupril may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking Accupril?

Do not use this medication if you are allergic to Accupril or to any other ACE inhibitor, such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), ramipril (Altace), or trandolapril (Mavik).

Before using Accupril, tell your doctor if you are allergic to any drugs, or if you have:

·         kidney disease (or if you are on dialysis);

·         liver disease;

·         heart disease or congestive heart failure;

·         diabetes; or

·         a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.

If you have any of these conditions, you may not be able to use Accupril, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category D. Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Accupril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. Accupril can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Accupril?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Take each dose with a full glass of water.

Accupril can be taken with or without food.

Vomiting, diarrhea, or heavy sweating can cause you to become dehydrated. This can lead to very low blood pressure, electrolyte disorders, or kidney failure while you are taking Accupril. Drink 6 to 8 full glasses of water daily while you are taking this medication.

To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled visits to your doctor.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking Accupril. You may need to stop using the medicine for a short time.

If you are being treated for high blood pressure, keep using this medication even if you feel fine. High blood pressure often has no symptoms.

Store Accupril at room temperature away from moisture and heat.

What are the possible side effects of Accupril?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

·         feeling light-headed, fainting;

·         urinating more or less than usual, or not at all;

·         fever, chills, body aches, flu symptoms;

·         pale skin, easy bruising or bleeding;

·         severe blistering, peeling, and red skin rash;

·         tired feeling, muscle weakness, and pounding or uneven heartbeats;

·         chest pain;

·         swelling, rapid weight gain; or

·         jaundice (yellowing of the skin or eyes).

Less serious side effects may be more likely to occur, such as:

·         cough;

·         muscle pain;

·         dizziness, drowsiness, headache;

·         nausea, vomiting, diarrhea, stomach pain; or

·         mild skin itching or rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

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